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Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs

Ischemic heart disease, which is often associated with irreversibly damaged heart muscle, is a major global health burden. Here, we report the potential of stem cell-derived committed cardiac progenitors (CCPs) have in regenerative cardiology. Human pluripotent embryonic stem cells were differentiat...

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Detalles Bibliográficos
Autores principales: Yap, Lynn, Chong, Li Yen, Tan, Clarissa, Adusumalli, Swarnaseetha, Seow, Millie, Guo, Jing, Cai, Zuhua, Loo, Sze Jie, Lim, Eric, Tan, Ru San, Grishina, Elina, Soong, Poh Loong, Lath, Narayan, Ye, Lei, Petretto, Enrico, Tryggvason, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219927/
https://www.ncbi.nlm.nih.gov/pubmed/37236990
http://dx.doi.org/10.1038/s41536-023-00302-6