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Multimodal single cell analysis infers widespread enhancer co-activity in a lymphoblastoid cell line

Non-coding regulatory elements such as enhancers are key in controlling the cell-type specificity and spatio-temporal expression of genes. To drive stable and precise gene transcription robust to genetic variation and environmental stress, genes are often targeted by multiple enhancers with redundan...

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Detalles Bibliográficos
Autores principales: Ziyani, Chaymae, Delaneau, Olivier, Ribeiro, Diogo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219981/
https://www.ncbi.nlm.nih.gov/pubmed/37237005
http://dx.doi.org/10.1038/s42003-023-04954-4