Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2

Positional information encoded in signaling molecules is essential for early patterning in the prosensory domain of the developing cochlea. The sensory epithelium, the organ of Corti, contains an exquisite repeating pattern of hair cells and supporting cells. This requires precision in the morphogen...

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Detalles Bibliográficos
Autores principales: Thompson, Matthew J., Young, Caryl A., Munnamalai, Vidhya, Umulis, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219982/
https://www.ncbi.nlm.nih.gov/pubmed/37237002
http://dx.doi.org/10.1038/s41598-023-34725-4

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