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Early radial positional information in the cochlea is optimized by a precise linear BMP gradient and enhanced by SOX2
Positional information encoded in signaling molecules is essential for early patterning in the prosensory domain of the developing cochlea. The sensory epithelium, the organ of Corti, contains an exquisite repeating pattern of hair cells and supporting cells. This requires precision in the morphogen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10219982/ https://www.ncbi.nlm.nih.gov/pubmed/37237002 http://dx.doi.org/10.1038/s41598-023-34725-4 |