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Proteolytic Restriction of Chordin Range Underlies BMP Gradient Formation

A fundamental question in developmental biology is how morphogens, such as bone morphogenetic protein (BMP), form precise signaling gradients to impart positional and functional identity to the cells of the early embryo. We combine rigorous mutant analyses with quantitative immunofluorescence to det...

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Detalles Bibliográficos
Autores principales: Tuazon, Francesca B., Wang, Xu, Andrade, Jonathan Lee, Umulis, David, Mullins, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731995/
https://www.ncbi.nlm.nih.gov/pubmed/32814043
http://dx.doi.org/10.1016/j.celrep.2020.108039