Validation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes

BOADICEA is a comprehensive risk prediction model for breast and/or ovarian cancer (BC/OC) and for carrying pathogenic variants (PVs) in cancer susceptibility genes. In addition to BRCA1 and BRCA2, BOADICEA version 6 includes PALB2, CHEK2, ATM, BARD1, RAD51C and RAD51D. To validate its predictions f...

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Detalles Bibliográficos
Autores principales: Møller, Nanna Bæk, Boonen, Desirée Sofie, Feldner, Elisabeth Simone, Hao, Qin, Larsen, Martin, Lænkholm, Anne-Vibeke, Borg, Åke, Kvist, Anders, Törngren, Therese, Jensen, Uffe Birk, Boonen, Susanne Eriksen, Thomassen, Mads, Terkelsen, Thorkild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220031/
https://www.ncbi.nlm.nih.gov/pubmed/37237042
http://dx.doi.org/10.1038/s41598-023-35755-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220031/
https://www.ncbi.nlm.nih.gov/pubmed/37237042
http://dx.doi.org/10.1038/s41598-023-35755-8

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