Computational structural-based GPCR optimization for user-defined ligand: Implications for the development of biosensors

Organisms have developed effective mechanisms to sense the external environment. Human-designed biosensors exploit this natural optimization, where different biological machinery have been adapted to detect the presence of user-defined molecules. Specifically, the pheromone pathway in the model orga...

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Detalles Bibliográficos
Autores principales: Di Rienzo, Lorenzo, Miotto, Mattia, Milanetti, Edoardo, Ruocco, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220229/
https://www.ncbi.nlm.nih.gov/pubmed/37249971
http://dx.doi.org/10.1016/j.csbj.2023.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220229/
https://www.ncbi.nlm.nih.gov/pubmed/37249971
http://dx.doi.org/10.1016/j.csbj.2023.05.004

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