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Computational structural-based GPCR optimization for user-defined ligand: Implications for the development of biosensors
Organisms have developed effective mechanisms to sense the external environment. Human-designed biosensors exploit this natural optimization, where different biological machinery have been adapted to detect the presence of user-defined molecules. Specifically, the pheromone pathway in the model orga...
Autores principales: | Di Rienzo, Lorenzo, Miotto, Mattia, Milanetti, Edoardo, Ruocco, Giancarlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220229/ https://www.ncbi.nlm.nih.gov/pubmed/37249971 http://dx.doi.org/10.1016/j.csbj.2023.05.004 |
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