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A machine learning approach for identifying variables associated with risk of developing neutralizing antidrug antibodies to factor VIII

A key unmet need in the management of hemophilia A (HA) is the lack of clinically validated markers that are associated with the development of neutralizing antibodies to Factor VIII (FVIII) (commonly referred to as inhibitors). This study aimed to identify relevant biomarkers for FVIII inhibition u...

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Detalles Bibliográficos
Autores principales: Rawal, Atul, Kidchob, Christopher, Ou, Jiayi, Yogurtcu, Osman N., Yang, Hong, Sauna, Zuben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220358/
https://www.ncbi.nlm.nih.gov/pubmed/37251488
http://dx.doi.org/10.1016/j.heliyon.2023.e16331