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Structural dynamics reveal subtype-specific activation and inhibition of influenza virus hemagglutinin

Influenza hemagglutinin (HA) is a prototypical class 1 viral entry glycoprotein, responsible for mediating receptor binding and membrane fusion. Structures of its prefusion and postfusion forms, embodying the beginning and endpoints of the fusion pathway, have been extensively characterized. Studies...

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Detalles Bibliográficos
Autores principales: Garcia, Natalie K., Kephart, Sally M., Benhaim, Mark A., Matsui, Tsutomu, Mileant, Alexander, Guttman, Miklos, Lee, Kelly.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220487/
https://www.ncbi.nlm.nih.gov/pubmed/37121546
http://dx.doi.org/10.1016/j.jbc.2023.104765