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Investigation of Cellular Response to the HSP90 Inhibition in Human Cells Through Thermal Proteome Profiling

Heat shock proteins are chaperones, and they are responsible for protein folding in cells. Heat shock protein 90 (HSP90) is one of the most important chaperones in human cells, and its inhibition is promising for cancer therapy. However, despite the development of multiple HSP90 inhibitors, none of...

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Detalles Bibliográficos
Autores principales: Yin, Kejun, Wu, Ronghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220490/
https://www.ncbi.nlm.nih.gov/pubmed/37119972
http://dx.doi.org/10.1016/j.mcpro.2023.100560