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A Novel Targeted RIG-I Receptor 5′Triphosphate Double Strain RNA-Based Adjuvant Significantly Improves the Immunogenicity of the SARS-CoV-2 Delta-Omicron Chimeric RBD-Dimer Recombinant Protein Vaccine

The rapid mutation and spread of SARS-CoV-2 variants recently, especially through the emerging variants Omicron BA5, BF7, XBB and BQ1, necessitate the development of universal vaccines to provide broad spectrum protection against variants. For the SARS-CoV-2 universal recombinant protein vaccines, a...

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Detalles Bibliográficos
Autores principales: Bai, Yu, An, Chaoqiang, Zhang, Xuanxuan, Li, Kelei, Cheng, Feiran, Cui, Bopei, Song, Ziyang, Liu, Dong, Zhang, Jialu, He, Qian, Liu, Jianyang, Mao, Qunying, Liang, Zhenglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220529/
https://www.ncbi.nlm.nih.gov/pubmed/37243185
http://dx.doi.org/10.3390/v15051099