Tryptophanase Expressed by Salmonella Halts Breast Cancer Cell Growth In Vitro and Inhibits Production of Immunosuppressive Kynurenine

Tryptophan is an essential amino acid required for tumor cell growth and is also the precursor to kynurenine, an immunosuppressive molecule that plays a role in limiting anticancer immunity. Tryptophanase (TNase) is an enzyme expressed by different bacterial species that converts tryptophan into ind...

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Detalles Bibliográficos
Autores principales: Hababag, Eljoie Anice Cada, Cauilan, Allea, Quintero, David, Bermudes, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220722/
https://www.ncbi.nlm.nih.gov/pubmed/37317329
http://dx.doi.org/10.3390/microorganisms11051355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220722/
https://www.ncbi.nlm.nih.gov/pubmed/37317329
http://dx.doi.org/10.3390/microorganisms11051355

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