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GRP78 Inhibitor YUM70 Suppresses SARS-CoV-2 Viral Entry, Spike Protein Production and Ameliorates Lung Damage

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 pandemic, has given rise to many new variants with increased transmissibility and the ability to evade vaccine protection. The 78-kDa glucose-regulated protein (GRP78) is a major endoplasmic reticul...

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Detalles Bibliográficos
Autores principales: Ha, Dat P., Shin, Woo-Jin, Hernandez, Juan Carlos, Neamati, Nouri, Dubeau, Louis, Machida, Keigo, Lee, Amy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220750/
https://www.ncbi.nlm.nih.gov/pubmed/37243204
http://dx.doi.org/10.3390/v15051118