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2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles

A potent nontoxic antitumor drug, 2-hydroxyoleic acid (6, 2OHOA) used for membrane lipid therapy, was selected as a self-assembly inducer due to its ability to form nanoparticles (NPs) in water. For this purpose, it was conjugated with a series of anticancer drugs through a disulfide-containing link...

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Detalles Bibliográficos
Autores principales: Antoniou, Antonia I., Nordio, Giulia, Di Paolo, Maria Luisa, Colombo, Eleonora, Gaffuri, Beatrice, Polito, Laura, Amenta, Arianna, Seneci, Pierfausto, Dalla Via, Lisa, Perdicchia, Dario, Passarella, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220756/
https://www.ncbi.nlm.nih.gov/pubmed/37242505
http://dx.doi.org/10.3390/ph16050722