Cargando…

Recent Advances in Covalent Drug Discovery

In spite of the increasing number of biologics license applications, the development of covalent inhibitors is still a growing field within drug discovery. The successful approval of some covalent protein kinase inhibitors, such as ibrutinib (BTK covalent inhibitor) and dacomitinib (EGFR covalent in...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaefer, Daniel, Cheng, Xinlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220821/
https://www.ncbi.nlm.nih.gov/pubmed/37242447
http://dx.doi.org/10.3390/ph16050663