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Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5′-Nucleotidase Activity

Mesenchymal stem/stromal cell (MSC) exosomes have been shown to alleviate immune dysfunction and inflammation in preclinical animal models. This therapeutic effect is attributed, in part, to their ability to promote the polarization of anti-inflammatory M2-like macrophages. One polarization mechanis...

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Detalles Bibliográficos
Autores principales: Teo, Kristeen Ye Wen, Zhang, Shipin, Loh, Jia Tong, Lai, Ruenn Chai, Hey, Hwee Weng Dennis, Lam, Kong-Peng, Lim, Sai Kiang, Toh, Wei Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220822/
https://www.ncbi.nlm.nih.gov/pubmed/37242732
http://dx.doi.org/10.3390/pharmaceutics15051489