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Optimizing Vancomycin Therapy in Critically Ill Children: A Population Pharmacokinetics Study to Inform Vancomycin Area under the Curve Estimation Using Novel Biomarkers

Area under the curve (AUC)-directed vancomycin therapy is recommended, but Bayesian AUC estimation in critically ill children is difficult due to inadequate methods for estimating kidney function. We prospectively enrolled 50 critically ill children receiving IV vancomycin for suspected infection an...

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Detalles Bibliográficos
Autores principales: Downes, Kevin J., Zuppa, Athena F., Sharova, Anna, Neely, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220925/
https://www.ncbi.nlm.nih.gov/pubmed/37242578
http://dx.doi.org/10.3390/pharmaceutics15051336