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Molecular Structural Analysis of Porcine CMAH–Native Ligand Complex and High Throughput Virtual Screening to Identify Novel Inhibitors

Porcine meat is the most consumed red meat worldwide. Pigs are also vital tools in biological and medical research. However, xenoreactivity between porcine’s N-glycolylneuraminic acid (Neu5Gc) and human anti-Neu5Gc antibodies poses a significant challenge. On the one hand, dietary Neu5Gc intake has...

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Detalles Bibliográficos
Autores principales: Ogun, Oluwamayowa Joshua, Thaller, Georg, Becker, Doreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220980/
https://www.ncbi.nlm.nih.gov/pubmed/37242354
http://dx.doi.org/10.3390/pathogens12050684