Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models

The COVID-19 pandemic has underscored the importance of swift responses and the necessity of dependable technologies for vaccine development. Our team previously developed a fast cloning system for the modified vaccinia virus Ankara (MVA) vaccine platform. In this study, we reported on the construct...

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Detalles Bibliográficos
Autores principales: Lorenzo, María M., Marín-López, Alejandro, Chiem, Kevin, Jimenez-Cabello, Luis, Ullah, Irfan, Utrilla-Trigo, Sergio, Calvo-Pinilla, Eva, Lorenzo, Gema, Moreno, Sandra, Ye, Chengjin, Park, Jun-Gyu, Matía, Alejandro, Brun, Alejandro, Sánchez-Puig, Juana M., Nogales, Aitor, Mothes, Walther, Uchil, Pradeep D., Kumar, Priti, Ortego, Javier, Fikrig, Erol, Martinez-Sobrido, Luis, Blasco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220993/
https://www.ncbi.nlm.nih.gov/pubmed/37243110
http://dx.doi.org/10.3390/vaccines11051006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220993/
https://www.ncbi.nlm.nih.gov/pubmed/37243110
http://dx.doi.org/10.3390/vaccines11051006

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