Chromosomal Instability Causes Sensitivity to Polyamines and One-Carbon Metabolism

Aneuploidy, or having a disrupted genome, is an aberration commonly found in tumours but rare in normal tissues. It gives rise to proteotoxic stress as well as a stereotypical oxidative shift, which makes these cells sensitive to internal and environmental stresses. Using Drosophila as a model, we i...

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Detalles Bibliográficos
Autores principales: Islam, Anowarul, Shaukat, Zeeshan, Newman, David L., Hussain, Rashid, Ricos, Michael G., Dibbens, Leanne, Gregory, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221085/
https://www.ncbi.nlm.nih.gov/pubmed/37233683
http://dx.doi.org/10.3390/metabo13050642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221085/
https://www.ncbi.nlm.nih.gov/pubmed/37233683
http://dx.doi.org/10.3390/metabo13050642

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