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Biophysical Interactions Underpin the Emergence of Information in the Genetic Code

The genetic code conceals a ‘code within the codons’, which hints at biophysical interactions between amino acids and their cognate nucleotides. Yet, research over decades has failed to corroborate systematic biophysical interactions across the code. Using molecular dynamics simulations and NMR, we...

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Detalles Bibliográficos
Autores principales: Halpern, Aaron, Bartsch, Lilly R., Ibrahim, Kaan, Harrison, Stuart A., Ahn, Minkoo, Christodoulou, John, Lane, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221087/
https://www.ncbi.nlm.nih.gov/pubmed/37240774
http://dx.doi.org/10.3390/life13051129