A MD Simulation Prediction for Regulation of N-Terminal Modification on Binding of CD47 to CD172a in a Force-Dependent Manner

Cancer cells can evade immune surveillance through binding of its transmembrane receptor CD47 to CD172a on myeloid cells. CD47 is recognized as a promising immune checkpoint for cancer immunotherapy inhibiting macrophage phagocytosis. N-terminal post-translated modification (PTM) via glutaminyl cycl...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Fang, Liping, Guo, Pei, Fang, Ying, Wu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221095/
https://www.ncbi.nlm.nih.gov/pubmed/37241964
http://dx.doi.org/10.3390/molecules28104224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221095/
https://www.ncbi.nlm.nih.gov/pubmed/37241964
http://dx.doi.org/10.3390/molecules28104224

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