Investigation of N-Acetyltransferase 2-Mediated Drug Interactions of Amifampridine: In Vitro and In Vivo Evidence of Drug Interactions with Acetaminophen

Amifampridine is a drug used for the treatment of Lambert–Eaton myasthenic syndrome (LEMS) and was approved by the Food and Drug Administration (FDA) of the United States (US) in 2018. It is mainly metabolized by N-acetyltransferase 2 (NAT2); however, investigations of NAT2-mediated drug interaction...

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Detalles Bibliográficos
Autores principales: Park, Yeo-Dim, Chae, Yoon-Jee, Maeng, Han-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221159/
https://www.ncbi.nlm.nih.gov/pubmed/37242713
http://dx.doi.org/10.3390/pharmaceutics15051471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221159/
https://www.ncbi.nlm.nih.gov/pubmed/37242713
http://dx.doi.org/10.3390/pharmaceutics15051471

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