Assessment of Aptamer as a Potential Drug Targeted Delivery for Retinal Angiogenesis Inhibition

AT11-L0 is an aptamer derivative of AS1411 composed of G-rich sequences that can adopt a G-quadruplex (G4) structure and target nucleolin (NCL), a protein that acts as a co-receptor for several growth factors. Hence, this study aimed to characterize the AT11-L0 G4 structure and its interaction with...

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Detalles Bibliográficos
Autores principales: Moreira, David, Lopes-Nunes, Jéssica, Santos, Fátima Milhano, Campello, Maria Paula Cabral, Oliveira, Maria Cristina, Paulo, António, Tomaz, Cândida, Cruz, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221175/
https://www.ncbi.nlm.nih.gov/pubmed/37242534
http://dx.doi.org/10.3390/ph16050751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221175/
https://www.ncbi.nlm.nih.gov/pubmed/37242534
http://dx.doi.org/10.3390/ph16050751

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