LC-MS/MS Method for the Quantification of PARP Inhibitors Olaparib, Rucaparib and Niraparib in Human Plasma and Dried Blood Spot: Development, Validation and Clinical Validation for Therapeutic Drug Monitoring

Poly (ADP-ribose) polymerase inhibitors (PARPis) are becoming increasingly meaningful in oncology, and their therapeutic drug monitoring (TDM) might be beneficial for patients. Several bioanalytical methods have been reported for PARPis quantification in human plasma, but advantages might be obtaine...

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Detalles Bibliográficos
Autores principales: Canil, Giovanni, Orleni, Marco, Posocco, Bianca, Gagno, Sara, Bignucolo, Alessia, Montico, Marcella, Roncato, Rossana, Corsetti, Serena, Bartoletti, Michele, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221204/
https://www.ncbi.nlm.nih.gov/pubmed/37242766
http://dx.doi.org/10.3390/pharmaceutics15051524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221204/
https://www.ncbi.nlm.nih.gov/pubmed/37242766
http://dx.doi.org/10.3390/pharmaceutics15051524

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