Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes—A More Selective Anticancer Treatment?

Based on their drug delivery properties and activity against tumors, we combined PAMAM dendrimers with various platinum(IV) complexes in order to provide an improved approach of anticancer treatment. Platinum(IV) complexes were linked to terminal NH(2) moieties of PAMAM dendrimers of generation 2 (G...

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Detalles Bibliográficos
Autores principales: Lerchbammer-Kreith, Yvonne, Hejl, Michaela, Vician, Petra, Jakupec, Michael A., Berger, Walter, Galanski, Mathea S., Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221222/
https://www.ncbi.nlm.nih.gov/pubmed/37242758
http://dx.doi.org/10.3390/pharmaceutics15051515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221222/
https://www.ncbi.nlm.nih.gov/pubmed/37242758
http://dx.doi.org/10.3390/pharmaceutics15051515

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