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The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice

Neutralizing antibodies (nAbs), the popular antiviral drugs used for the treatment of COVID-19, are effective in reducing viral load and hospitalization. Currently, most nAbs are screened from convalescent or vaccinated individuals through single B-cell sequencing which requires cutting-edge facilit...

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Detalles Bibliográficos
Autores principales: An, Zhiyin, Zhang, Yu, Yu, Xiang, Xia, Jia, Yin, Yanan, Li, Guoming, Lu, Jing, Fan, Xuemei, Xu, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221228/
https://www.ncbi.nlm.nih.gov/pubmed/37242654
http://dx.doi.org/10.3390/pharmaceutics15051412