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Biological Activity of Optimized Codon Bovine Type III Interferon Expressed in Pichia pastoris

Type III interferons (IFN–λs) exhibit potent antiviral activity and immunomodulatory effects in specific cells. Nucleotide fragments of the bovine ifn–λ (boifn–λ) gene were synthetized after codon optimization. The boifn–λ gene was then amplified by splicing using overlap extension PCR (SOE PCR), re...

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Detalles Bibliográficos
Autores principales: An, Ran, Zhang, Runxiang, Guo, Yongli, Geng, Jinfeng, Si, Minglu, Wang, Shuangfeng, Gao, Mingchun, Wang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221290/
https://www.ncbi.nlm.nih.gov/pubmed/37243187
http://dx.doi.org/10.3390/v15051101