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An In Silico Approach toward the Appropriate Absorption Rate Metric in Bioequivalence
In bioequivalence, the maximum plasma concentration (Cmax) is traditionally used as a metric for the absorption rate, despite the fact that there are several concerns. The idea of “average slope” (AS) was recently introduced as an alternative metric to reflect absorption rate. This study aims to fur...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221334/ https://www.ncbi.nlm.nih.gov/pubmed/37242508 http://dx.doi.org/10.3390/ph16050725 |