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An In Silico Approach toward the Appropriate Absorption Rate Metric in Bioequivalence

In bioequivalence, the maximum plasma concentration (Cmax) is traditionally used as a metric for the absorption rate, despite the fact that there are several concerns. The idea of “average slope” (AS) was recently introduced as an alternative metric to reflect absorption rate. This study aims to fur...

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Detalles Bibliográficos
Autor principal: Karalis, Vangelis D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221334/
https://www.ncbi.nlm.nih.gov/pubmed/37242508
http://dx.doi.org/10.3390/ph16050725