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Fluorine-Functionalized Polyphosphazene Immunoadjuvant: Synthesis, Solution Behavior and In Vivo Potency

The inclusion of fluorine motifs in drugs and drug delivery systems is an established tool for modulating their biological potency. Fluorination can improve drug specificity or boost the vehicle’s ability to cross cellular membranes. However, the approach has yet to be applied to vaccine adjuvants....

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Detalles Bibliográficos
Autores principales: Tagad, Harichandra D., Marin, Alexander, Wang, Ruixue, Yunus, Abdul S., Fuerst, Thomas R., Andrianov, Alexander K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221343/
https://www.ncbi.nlm.nih.gov/pubmed/37241958
http://dx.doi.org/10.3390/molecules28104218