Highly Selective Targeting of Pancreatic Cancer in the Liver with a Near-Infrared Anti-MUC5AC Probe in a PDOX Mouse Model: A Proof-of-Concept Study

Accurately identifying metastatic disease is critical to directing the appropriate treatment in pancreatic cancer. Mucin 5AC is overexpressed in pancreatic cancer but absent in normal pancreas tissue. The present proof-of-concept study demonstrates the efficacy of an anti-mucin 5AC antibody conjugat...

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Detalles Bibliográficos
Autores principales: Turner, Michael A., Cox, Kristin E., Neel, Nicholas, Amirfakhri, Siamak, Nishino, Hiroto, Clary, Bryan M., Hosseini, Mojgan, Natarajan, Gopalakrishnan, Mallya, Kavita, Mohs, Aaron M., Hoffman, Robert M., Batra, Surinder K., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221372/
https://www.ncbi.nlm.nih.gov/pubmed/37241027
http://dx.doi.org/10.3390/jpm13050857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221372/
https://www.ncbi.nlm.nih.gov/pubmed/37241027
http://dx.doi.org/10.3390/jpm13050857

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