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Highly Selective Targeting of Pancreatic Cancer in the Liver with a Near-Infrared Anti-MUC5AC Probe in a PDOX Mouse Model: A Proof-of-Concept Study
Accurately identifying metastatic disease is critical to directing the appropriate treatment in pancreatic cancer. Mucin 5AC is overexpressed in pancreatic cancer but absent in normal pancreas tissue. The present proof-of-concept study demonstrates the efficacy of an anti-mucin 5AC antibody conjugat...
Autores principales: | Turner, Michael A., Cox, Kristin E., Neel, Nicholas, Amirfakhri, Siamak, Nishino, Hiroto, Clary, Bryan M., Hosseini, Mojgan, Natarajan, Gopalakrishnan, Mallya, Kavita, Mohs, Aaron M., Hoffman, Robert M., Batra, Surinder K., Bouvet, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221372/ https://www.ncbi.nlm.nih.gov/pubmed/37241027 http://dx.doi.org/10.3390/jpm13050857 |
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