The Specific Binding and Promotion Effect of Azoles on Human Aldo-Keto Reductase 7A2

Human AKR 7A2 broadly participates in the metabolism of a number of exogenous and endogenous compounds. Azoles are a class of clinically widely used antifungal drugs, which are usually metabolized by CYP 3A4, CYP2C19, and CYP1A1, etc. in vivo. The azole–protein interactions that human AKR7A2 partici...

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Detalles Bibliográficos
Autores principales: Wu, Wanying, Jiang, Tianqing, Lin, Haihui, Chen, Chao, Wang, Lingling, Wen, Jikai, Wu, Jun, Deng, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221418/
https://www.ncbi.nlm.nih.gov/pubmed/37233642
http://dx.doi.org/10.3390/metabo13050601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221418/
https://www.ncbi.nlm.nih.gov/pubmed/37233642
http://dx.doi.org/10.3390/metabo13050601

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