Isolation of Nocuolin A and Synthesis of New Oxadiazine Derivatives. Design, Synthesis, Molecular Docking, Apoptotic Evaluation, and Cathepsin B Inhibition

Nocuolin A (1), an oxadiazine, was isolated from the cyanobacterium Nostoc sp. Its chemical structure was elucidated using NMR and mass spectroscopic data. From this compound, two new oxadiazines, 3-[(6R)-5,6-dihydro-4,6-dipentyl-2H-1,2,3-oxadiazin-2-yl]-3-oxopropyl acetate (2) and 4-{3-[(6R)-5,6-di...

Descripción completa

Detalles Bibliográficos
Autores principales: Tena Pérez, Víctor, Apaza Ticona, Luis, H. Cabanillas, Alfredo, Maderuelo Corral, Santiago, Rosero Valencia, Diego Fernando, Martel Quintana, Antera, Ortega Domenech, Montserrat, Rumbero Sánchez, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221466/
https://www.ncbi.nlm.nih.gov/pubmed/37233478
http://dx.doi.org/10.3390/md21050284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221466/
https://www.ncbi.nlm.nih.gov/pubmed/37233478
http://dx.doi.org/10.3390/md21050284

Ejemplares similares