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Isolation of Nocuolin A and Synthesis of New Oxadiazine Derivatives. Design, Synthesis, Molecular Docking, Apoptotic Evaluation, and Cathepsin B Inhibition

Nocuolin A (1), an oxadiazine, was isolated from the cyanobacterium Nostoc sp. Its chemical structure was elucidated using NMR and mass spectroscopic data. From this compound, two new oxadiazines, 3-[(6R)-5,6-dihydro-4,6-dipentyl-2H-1,2,3-oxadiazin-2-yl]-3-oxopropyl acetate (2) and 4-{3-[(6R)-5,6-di...

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Detalles Bibliográficos
Autores principales:	Tena Pérez, Víctor, Apaza Ticona, Luis, H. Cabanillas, Alfredo, Maderuelo Corral, Santiago, Rosero Valencia, Diego Fernando, Martel Quintana, Antera, Ortega Domenech, Montserrat, Rumbero Sánchez, Ángel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221466/ https://www.ncbi.nlm.nih.gov/pubmed/37233478 http://dx.doi.org/10.3390/md21050284

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