A Dual-Approach Strategy to Optimize the Safety and Efficacy of Anti-Zika Virus Monoclonal Antibody Therapeutics

Antibody-dependent enhancement of infection (ADE) is clinically relevant to Dengue virus (DENV) infection and poses a major risk to the application of monoclonal antibody (mAb)-based therapeutics against related flaviviruses such as the Zika virus (ZIKV). Here, we tested a two-tier approach for sele...

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Detalles Bibliográficos
Autores principales: Sun, Haiyan, Yang, Ming, Lai, Huafang, Neupane, Biswas, Teh, Audrey Y.-H., Jugler, Collin, Ma, Julian K.-C., Steinkellner, Herta, Bai, Fengwei, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221487/
https://www.ncbi.nlm.nih.gov/pubmed/37243242
http://dx.doi.org/10.3390/v15051156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221487/
https://www.ncbi.nlm.nih.gov/pubmed/37243242
http://dx.doi.org/10.3390/v15051156

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