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A short‐chain carbonyl reductase mutant is an efficient catalyst in the production of (R)‐1,3‐butanediol

R‐1,3‐butanediol (R‐1,3‐BDO) is an important chiral intermediate of penem and carbapenem synthesis. Among the different synthesis methods to obtain pure enantiomer R‐1,3‐BDO, oxidation–reduction cascades catalysed by enzymes are promising strategies for its production. Dehydrogenases have been used...

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Detalles Bibliográficos
Autores principales: Guo, Xiaoyan, Gao, Yunfang, Liu, Fangzheng, Tao, Yong, Jin, Haibo, Wang, Jianjun, Wu, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221522/
https://www.ncbi.nlm.nih.gov/pubmed/36946330
http://dx.doi.org/10.1111/1751-7915.14249