Developing a metabolic model‐based fed‐batch feeding strategy for Pichia pastoris fermentation through fine‐tuning of the methanol utilization pathway

Pichia pastoris is a commonly used microbial host for recombinant protein production. It is mostly cultivated in fed‐batch mode, in which the environment of the cell is continuously changing. Hence, it is vital to understand the influence of feeding strategy parameters on the intracellular reaction...

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Detalles Bibliográficos
Autores principales: Boojari, Mohammad Amin, Rajabi Ghaledari, Fatemeh, Motamedian, Ehsan, Soleimani, Mehdi, Shojaosadati, Seyed Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221529/
https://www.ncbi.nlm.nih.gov/pubmed/37093126
http://dx.doi.org/10.1111/1751-7915.14264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221529/
https://www.ncbi.nlm.nih.gov/pubmed/37093126
http://dx.doi.org/10.1111/1751-7915.14264

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