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Construction of a Yeast Cell-Based Assay System to Analyze SNAP25-Targeting Botulinum Neurotoxins

Herein, we describe a yeast cell-based assay system to analyze SNAP25-targeting botulinum neurotoxins (BoNTs). BoNTs are protein toxins, and, upon incorporation into neuronal cells, their light chains (BoNT-LCs) target specific synaptosomal N-ethylmaleimide-sensitive attachment protein receptor (SNA...

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Detalles Bibliográficos
Autores principales: Chen, Shilin, Li, Feng, Liu, Guoyu, Li, Yuqing, Li, Zijie, Liu, Yishi, Nakanishi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221579/
https://www.ncbi.nlm.nih.gov/pubmed/37317099
http://dx.doi.org/10.3390/microorganisms11051125