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Construction of a Yeast Cell-Based Assay System to Analyze SNAP25-Targeting Botulinum Neurotoxins
Herein, we describe a yeast cell-based assay system to analyze SNAP25-targeting botulinum neurotoxins (BoNTs). BoNTs are protein toxins, and, upon incorporation into neuronal cells, their light chains (BoNT-LCs) target specific synaptosomal N-ethylmaleimide-sensitive attachment protein receptor (SNA...
Autores principales: | Chen, Shilin, Li, Feng, Liu, Guoyu, Li, Yuqing, Li, Zijie, Liu, Yishi, Nakanishi, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221579/ https://www.ncbi.nlm.nih.gov/pubmed/37317099 http://dx.doi.org/10.3390/microorganisms11051125 |
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