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Mono-(2-ethylhexyl) Phthalate (MEHP)-Induced Telomere Structure and Function Disorder Mediates Cell Cycle Dysregulation and Apoptosis via c-Myc and Its Upstream Transcription Factors in a Mouse Spermatogonia-Derived (GC-1) Cell Line

As a typical environmental endocrine disrupting chemical (EDC), di-(2-ethylhexyl) phthalate (DEHP) is thought to be related to reproductive disorders, especially in males. Growing evidence suggests that various EDCs may result in an impaired telomere structure and function, which is associated with...

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Detalles Bibliográficos
Autores principales: Zhou, Fangji, Guo, Chengwei, Wang, Lingqiao, Zhang, Guowei, Wang, Jia, Chen, Weiyan, Cui, Ke, Tan, Yao, Zhou, Ziyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221830/
https://www.ncbi.nlm.nih.gov/pubmed/37235262
http://dx.doi.org/10.3390/toxics11050448