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CH vs. HC—Promiscuous Metal Sponges in Antimicrobial Peptides and Metallophores

Histidine and cysteine residues, with their imidazole and thiol moieties that deprotonate at approximately physiological pH values, are primary binding sites for Zn(II), Ni(II) and Fe(II) ions and are thus ubiquitous both in peptidic metallophores and in antimicrobial peptides that may use nutrition...

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Detalles Bibliográficos
Autores principales: Garstka, Kinga, Dzyhovskyi, Valentyn, Wątły, Joanna, Stokowa-Sołtys, Kamila, Świątek-Kozłowska, Jolanta, Kozłowski, Henryk, Barceló-Oliver, Miquel, Bellotti, Denise, Rowińska-Żyrek, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221980/
https://www.ncbi.nlm.nih.gov/pubmed/37241727
http://dx.doi.org/10.3390/molecules28103985