Differential Blood–Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro

The blood–brain barrier (BBB) poses major challenges to drug delivery to the CNS. SFTI-1 and kalata B1 are cyclic cell-penetrating peptides (cCPPs) with high potential to be used as scaffolds for drug delivery. We here studied their transport across the BBB and distribution within the brain to gauge...

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Detalles Bibliográficos
Autores principales: Melander, Erik, Eriksson, Camilla, Wellens, Sara, Hosseini, Kimia, Fredriksson, Robert, Gosselet, Fabien, Culot, Maxime, Göransson, Ulf, Hammarlund-Udenaes, Margareta, Loryan, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222203/
https://www.ncbi.nlm.nih.gov/pubmed/37242750
http://dx.doi.org/10.3390/pharmaceutics15051507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222203/
https://www.ncbi.nlm.nih.gov/pubmed/37242750
http://dx.doi.org/10.3390/pharmaceutics15051507

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