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Differential Blood–Brain Barrier Transport and Cell Uptake of Cyclic Peptides In Vivo and In Vitro
The blood–brain barrier (BBB) poses major challenges to drug delivery to the CNS. SFTI-1 and kalata B1 are cyclic cell-penetrating peptides (cCPPs) with high potential to be used as scaffolds for drug delivery. We here studied their transport across the BBB and distribution within the brain to gauge...
Autores principales: | Melander, Erik, Eriksson, Camilla, Wellens, Sara, Hosseini, Kimia, Fredriksson, Robert, Gosselet, Fabien, Culot, Maxime, Göransson, Ulf, Hammarlund-Udenaes, Margareta, Loryan, Irena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222203/ https://www.ncbi.nlm.nih.gov/pubmed/37242750 http://dx.doi.org/10.3390/pharmaceutics15051507 |
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