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p53 at the Crossroads between Doxorubicin-Induced Cardiotoxicity and Resistance: A Nutritional Balancing Act

Doxorubicin (DOX) is a highly effective chemotherapeutic drug, but its long-term use can cause cardiotoxicity and drug resistance. Accumulating evidence demonstrates that p53 is directly involved in DOX toxicity and resistance. One of the primary causes for DOX resistance is the mutation or inactiva...

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Detalles Bibliográficos
Autores principales: Guo, Yuanfang, Tang, Yufeng, Lu, Guangping, Gu, Junlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222243/
https://www.ncbi.nlm.nih.gov/pubmed/37242146
http://dx.doi.org/10.3390/nu15102259