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Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants

Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in swelling, stiffness, and joint pain. TAM receptors (Tyro3, Axl, and Mer) play an important role in regulating immune responses, clearing apoptotic c...

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Detalles Bibliográficos
Autores principales: Vago, Juliana P., Valdrighi, Natália, Blaney-Davidson, Esmeralda N., Hornikx, Daniel L. A. H., Neefjes, Margot, Barba-Sarasua, María E., Thielen, Nathalie G. M., van den Bosch, Martijn H. J., van der Kraan, Peter M., Koenders, Marije I., Amaral, Flávio A., van de Loo, Fons A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222253/
https://www.ncbi.nlm.nih.gov/pubmed/37242486
http://dx.doi.org/10.3390/ph16050703