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Gas6/Axl Axis Activation Dampens the Inflammatory Response in Osteoarthritic Fibroblast-like Synoviocytes and Synovial Explants
Osteoarthritis (OA) is the most prevalent joint disease, and it is characterized by cartilage degeneration, synovitis, and bone sclerosis, resulting in swelling, stiffness, and joint pain. TAM receptors (Tyro3, Axl, and Mer) play an important role in regulating immune responses, clearing apoptotic c...
Autores principales: | Vago, Juliana P., Valdrighi, Natália, Blaney-Davidson, Esmeralda N., Hornikx, Daniel L. A. H., Neefjes, Margot, Barba-Sarasua, María E., Thielen, Nathalie G. M., van den Bosch, Martijn H. J., van der Kraan, Peter M., Koenders, Marije I., Amaral, Flávio A., van de Loo, Fons A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222253/ https://www.ncbi.nlm.nih.gov/pubmed/37242486 http://dx.doi.org/10.3390/ph16050703 |
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