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HuNoV Non-Structural Protein P22 Induces Maturation of IL-1β and IL-18 and N-GSDMD-Dependent Pyroptosis through Activating NLRP3 Inflammasome

Norovirus infection is the leading cause of foodborne gastroenteritis worldwide, causing more than 200,000 deaths each year. As a result of a lack of reproducible and robust in vitro culture systems and suitable animal models for human norovirus (HuNoV) infection, the pathogenesis of HuNoV is still...

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Detalles Bibliográficos
Autores principales: Chen, Nini, Chen, Peiyu, Zhou, Yanhe, Chen, Sidong, Gong, Sitang, Fu, Ming, Geng, Lanlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222306/
https://www.ncbi.nlm.nih.gov/pubmed/37243097
http://dx.doi.org/10.3390/vaccines11050993