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5-Chloro-2-Guanidinobenzimidazole (ClGBI) Is a Non-Selective Inhibitor of the Human H(V)1 Channel

5-chloro-2-guanidinobenzimidazole (ClGBI), a small-molecule guanidine derivative, is a known effective inhibitor of the voltage-gated proton (H(+)) channel (H(V)1, K(d) ≈ 26 μM) and is widely used both in ion channel research and functional biological assays. However, a comprehensive study of its io...

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Detalles Bibliográficos
Autores principales: Szanto, Tibor G., Feher, Adam, Korpos, Eva, Gyöngyösi, Adrienn, Kállai, Judit, Mészáros, Beáta, Ovari, Krisztian, Lányi, Árpád, Panyi, Gyorgy, Varga, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222378/
https://www.ncbi.nlm.nih.gov/pubmed/37242439
http://dx.doi.org/10.3390/ph16050656